Development and Validation for RP-HPLC Method of Assay of Omeprazole Capsules Formulation

Development and Validation of RP-HPLC-UV Method for Determination of Diclofenac Sodium Residues on Surfaces for Cleaning Validation

In recent years, cleaning validation has achieved a position of increasing in the pharmaceutical industry. It provides assurance to the cleaning procedure that ensures equipment is consistently cleaned from the product, detergent and microbial residues to an acceptable level to avoid cross-contamination and adulteration of drug product with other active ingredients. The aim of this study was to...

Development and Validation of RP-HPLC Method for Analysis of Novel Self-emulsifying Paclitaxel Formulation

A stability indicating liquid chromatography method was developed and validated for quantitation of aliquots of the in-vitro drug release and ex-vivo permeation study for paclitaxel in a new pharmaceutical dosage form. The reverse phase high performance liquid chromatography separation was achieved on C18 LiChrospher100 (250x4.6mm, 5 μm particle size) using a mobile phase of acetonitrile: wate...

Development and validation of RP-HPLC method for analysis of multicomponent cough-cold syrup formulation

In this study a reversed phase HPLC method for rapid and simultaneous identification and quantification of doxylamine succinate, ephedrine sulfate, dextrometorphane hydrobromide, paracetamole and sodium benzoate in cough-cold syrup formulation was described. Separation was carried out on XTerra RP 18, Waters (150 mm x 4.6 mm column, 5 μm particle size). For the analysis of investigated substanc...

development and validation of a new hplc analytical method for the quality control of clindamycin capsules

Development and validation of a fast, simple and specific stability indicating RP-HPLC method for determination of Dexpanthenol in eye gel formulation.

AIn this study a simple and reliable stability-indicating RP-HPLC method was developed and validated for analysis of Dexpanthenol in an artificial tear formulation. The chromatographic separation was performed on a HPLC C18 column (25.0 cm  4.6 mm, 5 m) using a mixture of 0.037 M monobasic potassium phosphate in water (adjusted with 0.1% (v/v) phosphoric acid to a pH of 3.2) and methanol (90:...